Mario Scaramella (born April 23, 1970 ) is an Italian lawyer and self-styled security consultant who came to international prominence in 2006 in connection with the poisoning of the ex-FSB agent Alexander Litvinenko. He served as an investigator and adviser to the controversial Mitrokhin Commission set up by Silvio Berlusconi's Forza Italia party in order to investigate supposed links between Berlusconi's political rivals, including his rival for the premiership (now Prime Minister) Romano Prodi and the KGB. Scaramella is alleged to have collaborated with the president of the commission Paolo Guzzanti in garnering false evidence to link Prodi with the KGB. Prodi has said he intends to sue over the allegations. Scaramella is currently under investigation by the Italian justice department for calumny and illegal weapons trade, accusations which Scaramella has replied to in an interview in L'Espresso.

While working for the Mitrokhin Commission, Scaramella claimed a Ukrainian ex-KGB agent living in Naples, Alexander Talik, conspired with three other Ukrainians to assassinate him and Senator Guzzanti. The Ukrainians were arrested, but Talik claimed that Scaramella had invented the story of the assassination attempt, which brought the calumny charge on him. Talik also claimed that rocket propelled grenades sent to him in Italy had in fact been sent by Scaramella himself.