Love in the Time of Cholera is a 2007 motion picture directed by Mike Newell. Based on the novel of the same name by Gabriel Garcia Márquez, it tells the story of a love triangle between Fermina Daza (played by Giovanna Mezzogiorno) and her two suitors, Florentino Ariza (Javier Bardem) and Doctor Juvenal Urbino (Benjamin Bratt) which spans 50 years, from 1880 to 1930.

Producer Scott Steindorff spent over three years courting Gabriel Garcia Márquez for the rights to the book telling him that he was Florentino and wouldn't give up until he got the rights.

It is the first filming of a Garcia Márquez novel by a Hollywood studio, rather than by Latin American or Italian directors. It is also the first English language work of Academy Award-nominated Brazilian actress Fernanda Montenegro.

Producer Scott Steindorff spent over 3 years courting Gabriel García Márquez (I) for the rights to the book telling him that he was Florentino and wouldn't give up until he got the rights.

For the days of shooting in Cartagena, Giovanna Mezzogiorno was given an entire beautiful old house to live in. One night, she heard some strange noises behind a closet and thought it was a ghost. When help arrived and investigated, they encountered with an owl's nest. Two owls were found and later named after the main characters of the movie, Florentino and Fermina.

Was initially set to be filmed in Brazil because of security concerns in Colombia.